Barbara Kingsolver’s novel “Demon Copperhead,” a riff on “David Copperfield” that moves Charles Dickens’s story to contemporary Appalachia and grapples engagingly with topics from poverty to ambition to opioid addiction, was one of the Book Review’s 10 Best Books of 2022. And — unlike an actual copperhead — “Demon Copperhead” has legs: Many readers have told us it was their favorite book in 2023 as well.

In this week’s spoiler-filled episode, MJ Franklin talks with Elisabeth Egan (an editor at the Book Review) and Anna Dubenko, the Times’s newsroom audience director, about their reactions to Kingsolver’s novel and why it has exerted such a lasting appeal.